A minibus carrying a group of women has been involved in a motorway crash with a lorry leaving multiple injuries.
Firefighters, paramedics and at least six air ambulances are at the scene of the collision on the M62 in Pontefract, West Yorkshire.
A number of casualties remain trapped in the wreckage of the minibus.
The collision happened on the M62 westbound, near junction 32. Yorkshire Ambulance said there are at least 25 injuries, some serious.
Picture by Leon Butler Police said the incident had left the motorway closed in both directions and advised motorists to avoid the area.
One man - believed to be the driver of the lorry - has been arrested. The women in the minibus are believed to be from the local area.
Assistant Chief Constable Craig Guildford of West Yorkshire Police, said: "This is a significant incident with a number of casualties and as a result of this we have had to close the motorway to allow emergency services to safely get to and free those who are injured.
"We realise this will cause disruption and I would ask drivers to bear with us and avoid the motorway in that area as there will be significant delays.
"Emergency Services remain on the scene and will re-open lanes of the M62 in the area as soon as we can do so safely, but clearly the priority at this stage has been recovering those who are injured.
"Anyone who is concerned about a family member or who has witnessed the collision itself is asked to contact West Yorkshire Police on 101 for information."
A spokeswoman for the Yorkshire Ambulance Service NHS Trust said: "We received an emergency call at 11.31am today to reports of a serious collision between a mini-coach and an HGV at junction 32 of the M62, close to Castleford, West Yorkshire.
"Due to the scale of the incident we have enacted our major incident plan and dispatched a number of resources to the scene including ambulances, our hazardous area response team, doctors and air ambulance.
"At this time we can confirm that we have treated and transported 25 patients and are working in close partnership with hospitals in the area, including Pinderfields Hospital in Wakefield and Leeds General Infirmary."
One man who was stuck in traffic on the motorway tweeted: "Nine ambulances 4 fire engines and god knows how many police cars have gone past."
The motorway is not expected to reopen until at least 6pm.
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