Three men have been killed after a double-decker coach collided with their stationary car on the M1 in Bedfordshire.
Their vehicle was on the hard shoulder between junctions 12 and 13 when the collision occurred at 6.46am this morning.
A fourth man has been taken to a hospital in Oxford with serious injuries, and the northbound carriageway of the M1 remains closed.
Meanwhile, at least one person has died in a pile-up on the M40. Another six people are seriously hurt, and as many as 45 people have been left with minor injuries.
The crash occurred just before 7.50am this morning on the northbound carriageway between junctions 9 and 10 in Bicester, Oxfordshire. An estimated 40 cars were involved.
That stretch of the motorway has been closed by the emergency services, and is not expected to open until 2.30pm. A couple of southbound lanes have now reopened.
"It is quite a major collision. We have a lot of resources on the scene - ambulances, our helicopter ambulance, rapid response vehicles, our doctor and our hazardous area response team," a spokeswoman for the South Central Ambulance Service said.
According to the Met Office, it was "quite foggy" on the roads this morning, and this would have hampered visibility considerably.
Traffic was already busier than usual on the M40 as families began their travels for the half-term holidays.
West Ham fans had been advised to avoid both motorways as they travelled to the Midlands to watch their team play West Brom.
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